RFI: Anthelmintic activity of medicinal plants (2)
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Dr Lateef,
Here are four abstracts of articles included in ExtraMED on
anthelmintic activity, which might be of use - please let me know if
you want the full text from ExtraMED.
Regards,
Chris
Chris Zielinski
CEO, Informania Ltd (ExtraMED)
P.O. Box 40
Petersfield, Hants GU32 2YH, United Kingdom
Tel: +44-1730-301-297
Fax: +44-1730-265-398
mailto:dvt@compuserve.com
http://www.iwsp.org
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ExtraMED Article
ExtraMED Number (EXN): 0253761395800085
Journal Title (JTI): Indian Journal of Pharmacology
Article Title (ATI): Possible mechanism of anthelmintic action of pa-
lasonin on Ascaridia galli
Author(s) (ATH): Kumar_D, Mishra_S_K, Tandan_S_K, Tripathi_H_C
International Standard Serial Number (ISN): 0253-7613
Year of publication (YPB): 1995
Volume number (VON): 27
Issue number (IUN): 3
Page range (PGR): 161-166
Number of pages (PGN): 6
Series or part number (SPN):
ExtraMED CD-ROM number (CDN): 15
Serial issue number (SEI): 970015 277840142 6
Keywords (KWD): Palasonin Anthelmintic action Biochemical basis As-
caridia galli
Abstract (ABS): The biochemical mechanism of anthelmintic action of
palasonin the active principle of Butea frondosa seeds has been in-
vestigated on Ascardia galli. Palasonin inhibited the glucose uptake
and depleted the glycogen content in the presence of glucose indicat-
ing that palasonin affects the energy generating mechanism of the
parasite. It also significantly increased the lactic acid suggesting
inhibition of ATP production or accumulation of lactic acid. Pa-
lasonin had no effect on AChE activity, though it potentiated the
spasmogenic effect of ACh on toad Rectus abdominis muscle. The fre-
quency and magnitude of spontaneous contractions of A. galli were
significantly inhibited by palasonin. Following 20 h incubation of A.
galli with palasonin, a significant inhibition in the gross visual
motility was also observed. In conclusion, the possible mechanism of
anthelmintic action of palasonin may be related to either inhibition
of energy metabolism and/or alteration in the motor activity of the
parasite.
Language (LAN): English
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ExtraMED Article
ExtraMED Number (EXN): 1110131895800166
Journal Title (JTI): Mansoura Journal of Pharmaceutical Sciences
Article Title (ATI): Biotransformation of a-santonin
Author(s) (ATH): El-Sharkawy_S, Zaghloul_A_M, Badria_F_A, Matooq_G_T
International Standard Serial Number (ISN): 1110-1318
Year of publication (YPB): 1996
Volume number (VON): 12
Issue number (IUN): 1
Page range (PGR): 99-109
Number of pages (PGN): 11
Series or part number (SPN):
ExtraMED CD-ROM number (CDN): 15
Serial issue number (SEI): 970015 169611440 11
Keywords (KWD): a-santonin Biotransformation Antimicrobial and
anthelmintic
Abstract (ABS): Bacillus cereus UI-1477 was able to convert a-
santonin into 1,2-dihydrosantonin in a 64% yield. The chemical iden-
tity of the obtained metabolite was confirmed by UV, IR, 1D- and 2D-,
^1H-,-, ^1^3-NMRC-NMR spectroscopy. Biological evaluation showed a
complete loss of both anthelmintic and antimicrobial activity of 1,2-
dihydrosantonin in comparison to a-santonin. Language (LAN): English
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ExtraMED Article
ExtraMED Number (EXN): 1110131898000055
Journal Title (JTI): Mansoura Journal of Pharmaceutical Sciences
Article Title (ATI): Synthesis of certain benzothiazole derivatives
to be evaluated as anthelmintics
Author(s) (ATH): Yousef_M_Y, Eisa_H_M, Nasr_M_N, El-Bialy_S_A
International Standard Serial Number (ISN): 1110-1318
Year of publication (YPB): 1997
Volume number (VON): 13
Issue number (IUN): 1
Page range (PGR): 79-88
Number of pages (PGN): 10
Series or part number (SPN):
ExtraMED CD-ROM number (CDN): 19
Serial issue number (SEI): 980019 116450572 10
Keywords (KWD):
Abstract (ABS):
New derivatives of 6-nitro-2-substituted acetamidobenzothiazole
(2a,3a-e), 3-substituted 2-iminothiazolidin-4-one (4a-e) and 5-
arylidene-2-iminothiazolidin-4-one (5a-j) were prepared. The testing
for the anthelmintic activity of two of the newly prepared compounds
using the earthworm method showed that they produce a promising ef-
fect. The detailed synthesis, spectroscopic and biological data are
reported.
Language (LAN): English
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ExtraMED Article
ExtraMED Number (EXN): 025071889410017Y
Journal Title (JTI): Hamdard Medicus
Article Title (ATI): DETERMINATION OF MINERAL ELEMENTS IN MEDICINAL
PLANTS USED FOR THE CURE OF BRONCHITIS, KIDNEY AND BLADDER DISORDER,
SKIN DISEASES AND GONORRHOEA ETC.
Author(s) (ATH): Sondhi_S_M, Agarwal_N
International Standard Serial Number (ISN): 0250-7188
Year of publication (YPB): 1995
Volume number (VON): XXXVIII
Issue number (IUN): 1
Page range (PGR): 24-29
Number of pages (PGN): 6
Series or part number (SPN):
ExtraMED CD-ROM number (CDN): 8
Serial issue number (SEI): 9408 111285676 6 CDN9408
Keywords (KWD):
Abstract (ABS): Determination of mineral elements in thirty-two me-
dicinal plants i.e Abroma augusta, Abutilon hirtum, Alocasia indica,
Argemone mexicana (Roots), Argemone mexicana (Seeds), Asteracantha
longifolia, Barleria prionitis, Barringtonia racemosa, Berberis
aristata, Caesalpinia crista, Cassia angustifolia, Centratherum
anthelminticum, Cissampelos pareira, Crataeva nurvala, Didymocarpus
pedicellata, Embelia ribes, Ficus carica, Hedychium spicatum, Helio-
trophium strigosum, Holarrhena antidysenterica, Ichnocarpus frutes-
cens, Justicia gendarussa, Lagenandra toxicaria. Mimusops elengi, Or-
chis mascula, Pedalium murex, Randia dumetorum, Sphaeranthus indicus,
Teramnus labialis, Tylophora indica, Verbascum thapsus and Vitis vi-
nifera used for the cure of bronchitis, kidney and bladder disorders,
skin diseases and gonorrhoea etc. have been carried out. Concentra-
tions of Na, K, Cu, Ni, Mn, Co, Zn, Cd, Fe, Pb,Mg, Cr, Ca, Hg, Al,
Ag, Sr, Mo and V were determined by using Flame Photometer (FPM),
Atomic Absorption Spectrometer (AAS) and Inductively Coupled Plasma
(ICP) respectively. Mineral elements Mn, Mg, Zn, Ca, Fe, Ni, Cr, Na,
K, Al and Sr are present in all the thirty-two medicinal plants.
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