# \[e-drug\] DNDi: Acoziborole -- Investigational single-dose oral treatment raises hope for elimination of sleeping sickness in Africa **URL:** \ **Category:** e-drug\ **Created:** [November 30, 2022, 6:08pm UTC](https://talk.edrugplus.org/t/e-drug-dndi-acoziborole-investigational-single-dose-oral-treatment-raises-hope-for-elimination-of-sleeping-sickness-in-africa/47005 "2022-11-30T18:08:01Z")\ **Posts on this page:** 1\ **Page:** 1
**Author:** ![Rachel\_Cohen](https://avatars.discourse-cdn.com/v4/letter/r/e480ec/32.png) [@Rachel\_Cohen](https://talk.edrugplus.org/u/Rachel_Cohen)\ **Post date:** [November 30, 2022, 6:08pm UTC](https://talk.edrugplus.org/t/e-drug-dndi-acoziborole-investigational-single-dose-oral-treatment-raises-hope-for-elimination-of-sleeping-sickness-in-africa/47005/1 "2022-11-30T18:08:01Z")
E-DRUG: DNDi: Acoziborole -- Investigational single-dose oral treatment raises hope for elimination of sleeping sickness in Africa ---------------------------------------------------------------------------- Dear colleagues, Today, DNDi announced results from a Phase II/III study on the safety and efficacy of single-dose acoziborole in the treatment of human African trypanosomiasis (HAT), which were also published in The Lancet Infectious Diseases. The clinical trial was led by DNDi and partners in the Democratic Republic of Congo (DRC) and Guinea and showed a treatment success rate after 18 months of up to 95%. For further information, please find: • Lancet ID paper: [https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00](https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00) 660-0/fulltext • An excellent comment piece in Lancet ID by Jacques Pépin: [https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00](https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00) 686-7/fulltext • DNDi press release: [https://dndi.org/press-releases/2022/acoziborole-investigational-si](https://dndi.org/press-releases/2022/acoziborole-investigational-si) ngle-dose-oral-treatment-raises-hope-elimination-sleeping-sickness/ If you are active on social media, we would be delighted if you would consider amplifying – here is the social media package: [https://bit.ly/socialmedia-acozi](https://bit.ly/socialmedia-acozi) Please let us know if you have any questions about this important milestone that will put us one step closer to sustainably eliminating HAT! Best, Rachel Cohen for DNDi \