# \[e-drug\] Generic substitution (cont'd)

**URL:** <https://talk.edrugplus.org/t/e-drug-generic-substitution-contd/17822>\
**Category:** e-drug\
**Created:** [October 7, 2003, 6:48am UTC](https://talk.edrugplus.org/t/e-drug-generic-substitution-contd/17822 "2003-10-07T06:48:06Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![Francisco\_Rossi](https://avatars.discourse-cdn.com/v4/letter/f/50afbb/32.png) [@Francisco\_Rossi](https://talk.edrugplus.org/u/Francisco_Rossi)\
**Post date:** [October 7, 2003, 6:48am UTC](https://talk.edrugplus.org/t/e-drug-generic-substitution-contd/17822/1 "2003-10-07T06:48:06Z")

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E-drug: Generic substitution (cont'd)  
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Dear friends:

I'm afraid the message was not clear enough. Of course the main  
target of our policy in Colombia is to reduce costs. And we are quite  
satisfied about the results. Our policy defines the "generic" choice. In  
other words the substitution option. No interchangeability. What is the  
difference? Usually when one talks about interchangeability, one talks  
about doing bio-bio tests as a general mandatory requirement.  
Substitution is only being able to choose between alternatives, and  
bio-bio tests are an exceptional requirement. Maybe this situation only  
exists in Latin America?

In narrow therapeutic window drugs you can select options, and we  
need a lot of options. Our recommendation is not to switch from one  
to another manufacturer, if possible. This is recommended for both  
generic and brandname drugs. And if necessary, only with carefully  
follow up.

Francisco A. Rossi. B.  
Advisor  
Ministerio de Protecci�n Social, Colombia  
Carrera 13 No 32-76  
Tel 57-1-3365066 ext 2229  
fax 57-1-3360165  
e-mail: francisco\_rossi@hotmail.com

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