# \[e-drug\] Prices of antimalarial combinations (cont'd)

**URL:** <https://talk.edrugplus.org/t/e-drug-prices-of-antimalarial-combinations-contd/12176>\
**Category:** e-drug\
**Created:** [August 18, 2001, 9:28am UTC](https://talk.edrugplus.org/t/e-drug-prices-of-antimalarial-combinations-contd/12176 "2001-08-18T09:28:10Z")\
**Posts on this page:** 1\
**Page:** 1

<div class="post-metadata">

**Author:** ![Dr\_S\_Toovey](https://avatars.discourse-cdn.com/v4/letter/d/71e660/32.png) [@Dr\_S\_Toovey](https://talk.edrugplus.org/u/Dr_S_Toovey)\
**Post date:** [August 18, 2001, 9:28am UTC](https://talk.edrugplus.org/t/e-drug-prices-of-antimalarial-combinations-contd/12176/1 "2001-08-18T09:28:10Z")

</div>

E-drug: Prices of antimalarial combinations (cont'd)  
-------------------------------------------------------------------------

I would suggest that you contact Novartis to see if you can access  
their really cheap co-artemether (artemether plus benflumetol - now  
renamed lumefantrine). They are running a programme with WHO to  
provide co-artemether at cost price.

The pricing works out at US$2,00 per course.

I would certainly avoid sulphadoxine and pyrimethamine as high  
levels of resistance are reported from various regions in southern  
Africa (up to 60% in Kwa-Zulu-Natal). Cross resistance between the  
chlorproguanil and dapsone combination(lap-dap) and the  
pyrimethamine and dapsone combination (Fansidar) is quite likely  
too.

Amodiaquine is associated with significant and potentially fatal  
toxicity. Its use in developed countries would be unthinkable, and I  
think the same should apply to developing countries too.

My recommendation would be the choice of co-artemether if you  
can obtain it at preferential pricing from Novartis.

Dr Stephen Toovey  
SAA-Netcare Travel Clinics  
P O Box 786692  
Sandton 2146, South Africa  
Fax: +27-11-883-6152  
e-mail: toovey@travelclinic.co.za  
[http://www.travelclinic.co.za](http://www.travelclinic.co.za)  
[http://www.malaria.co.za](http://www.malaria.co.za)

--  
Send mail for the `E-Drug' conference to `e-drug@usa.healthnet.org'.  
Information and archive [http://satellife.healthnet.org/programs/edrug.html](http://satellife.healthnet.org/programs/edrug.html)  
Mail administrative requests to `majordomo@usa.healthnet.org'.  
For additional assistance, send mail to: `owner-e-drug@usa.healthnet.org'.
