# E-DRUG: Quinine **URL:** \ **Category:** e-drug\ **Created:** [March 30, 1997, 8:50pm UTC](https://talk.edrugplus.org/t/e-drug-quinine/548 "1997-03-30T20:50:59Z")\ **Posts on this page:** 1\ **Page:** 1
**Author:** ![Dr\_Eberhard\_W\_Lisse1](https://avatars.discourse-cdn.com/v4/letter/d/59ef9b/32.png) [@Dr\_Eberhard\_W\_Lisse1](https://talk.edrugplus.org/u/Dr_Eberhard_W_Lisse1)\ **Post date:** [March 30, 1997, 8:50pm UTC](https://talk.edrugplus.org/t/e-drug-quinine/548/1 "1997-03-30T20:50:59Z")
SK. > Chloroquin resistance is so high at the Kenyan Coast that we are in the > processs of removing it as a first line drug. In fact one of the major I can certainly understand this, we have a similar experience here (in the north, not where I live, we just get traveler's malaria), but we still don't want Quinine to be used by PHC, because the only thing that is going to happen if you give it as first line drug, is that you will develop Quinine resistant Malaria. Not something I'd like to contract :-)-O I still treat simple cases with Chloroquine (and a proteinsynthesis inhibitor such as doxycylin or erythromycin) under very close observation and only give quinine if I can demonstrate RI-III. > problems we have is chloroquin overdose. A child presents with fever and > the mother gives him chloroquin, the child does not improve and is taken > to a private clinic where he is also given chloroquin again and then > taken to a dispensary or a health centre or outpatient department of a > district or a subdistrict hospital where he is given chloroquin again. And? The same will happen to quinine. Why don't you educate your patients, or rather train the PHC staff? > Patients with complications of malaria such as hypoglycaemia,dehydration > convultions are treated with appropriate medications eg IV dextrose for > hypogycaemia,dehydration with IV fluids ,fits with diazepam.Quinine is > given IM ( or IV if he is going to receve IV fluids to correct > dehydration). At any one time the hospital has 10-15 children in the > paediatric ward with malaria and all of them on quinine. I still don't see the reason to give IMI. We give oral if they are not vomiting and composmentes and IVI if otherwise. > We had a difficult time convincing the staff about using IM quinine. So, the workload is not really the problem, isn't it? > We are now in the process of providing quinine to the rural health > facilities. I think this is a rather dangerous thing to do. > There have been studies on plasma levels after IM and IV quinine from > Gambia and Kenya.Will send you the references after the holidays. I'd like to see them and will send them to the man :-)-O > It is very encouraging to have the debate on quinine. Indeed, the regular stuff on this list is a bit dry and sometimes very PC :-)-O. > Maybe some expert on malaria will comment. Dr Lichtman is the Consultant in Charge of ICU at the National Hospital and very very experienced in severe and complicated Malaria. I'll communicate with him on this. > I am just physcian who deals with everything under the sun including > which includes all diseases including "syndrome of inadequate rsourses > for health" (SIRH). So am I, though on the other beach :-)-O. However SIRH isn't really affecting us yet. el -- Dr. Eberhard W. Lisse\ / Swakopmund State Hospital \ \* | Resident Medical Officer Private Bag 5004 \ / +264 81 124 6733 (cell) 64 461005(h) 461004(f) Swakopmund, Namibia ;\_\_\_\_/ Domain Coordinator for NA-DOM (el108) Vice-Chairman, Board of Trustees, Namibian Internet Development Foundation, an Association not for Gain. NAMIDEF is the Namibian Internet Service Provider. -- Send mail for the `E-Drug' conference to `e-drug@usa.healthnet.org'. Mail administrative requests to `majordomo@usa.healthnet.org'. For additional assistance, send mail to: `owner-e-drug@usa.healthnet.org'.