# \[e-drug\] Rational versus Appropriate Medicines Use

**URL:** <https://talk.edrugplus.org/t/e-drug-rational-versus-appropriate-medicines-use/28885>\
**Category:** e-drug\
**Created:** [November 25, 2007, 12:43pm UTC](https://talk.edrugplus.org/t/e-drug-rational-versus-appropriate-medicines-use/28885 "2007-11-25T12:43:34Z")\
**Posts on this page:** 4\
**Page:** 1

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**Author:** ![Chris\_Forshaw3](https://avatars.discourse-cdn.com/v4/letter/c/c2a13f/32.png) [@Chris\_Forshaw3](https://talk.edrugplus.org/u/Chris_Forshaw3)\
**Post date:** [November 25, 2007, 12:43pm UTC](https://talk.edrugplus.org/t/e-drug-rational-versus-appropriate-medicines-use/28885/1 "2007-11-25T12:43:34Z")

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E-DRUG: Rational versus Appropriate Medicines Use  
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Dear E-druggers

The ongoing debate on the Make Medicines Child Size slogan and the  
various proposed better alternatives has stimulated me to put forward a  
case for consideration of changing from Rational Medicines Use to  
Appropriate Medicines Use.

According to definitions gleaned from the numerous online dictionaries  
available the adjective rational is associated with reasonable, sensible  
and logical. Thus it would be rational for a patient to only buy a  
single days treatment of an antibiotic rather than a full 5-day course  
if that was all they could afford. It would also be rational for them to  
stop taking a medicine if they appeared to be cured or if they  
experienced unpleasant adverse effects. However in these cases it would  
certainly not be appropriate for them to behave this way in terms of  
obtaining the required and expected therapeutic benefit of the medicine.

On the other hand the word appropriate is associated with suitability  
and fitness for purpose or circumstances. This would therefore seem to  
be indeed much a more appropriate adjective when applied to medicines  
use.

The word could equally well be applied to the WHO childrens medicines  
campaign as in \>\>\>Make Medicines Appropriate for Children\<\<\<

Best regards

Chris Forshaw

Pharmaceutical Adviser  
Ministry of Health, Kenya  
c/o Royal Danish Embassy  
Box 40412-00100, Nairobi, Kenya

Mobile: +254 724 253 202  
Tel/fax (home): +254 20 206 2156  
Office direct: +254 20 272 4944  
forshaw@hsps.or.ke

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**Author:** ![Dr\_Peter\_R\_Mansfield](https://avatars.discourse-cdn.com/v4/letter/d/c68b51/32.png) [@Dr\_Peter\_R\_Mansfield](https://talk.edrugplus.org/u/Dr_Peter_R_Mansfield)\
**Post date:** [November 26, 2007, 6:51am UTC](https://talk.edrugplus.org/t/e-drug-rational-versus-appropriate-medicines-use/28885/2 "2007-11-26T06:51:17Z")

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E-DRUG: Rational versus Appropriate Medicines Use (2)  
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Dear E-druggers,

I agree with Chris Forshaw that "appropriate" is a more appropriate word than "rational". One of my reasons is that  
whilst many decisions are bad, few are irrational. Usually the logic is valid but based on information that is flawed,  
irrelevant and/or incomplete.

Another reason is that the word used can make a big difference to discussions about treatment choices that we disagree  
with. If we suggest that a treatment choice is irrational then we are suggesting that the person who made the choice is  
mentally deficient. This is not a good way to win friends and influence people! By contrast, if we suggest that a  
treatment choice is inappropriate then we are focusing on disagreements about aspects of the drug. The latter is more  
likely to be successful.

This is why in 1983 I named my organisation the Medical Lobby for Appropriate Marketing. Our name has been changed to  
Healthy Skepticism but we still work for appropriate medicines use.

regards,

Peter

Dr Peter R Mansfield OAM BMBS  
GP  
Director, Healthy Skepticism Inc  
www.healthyskepticism.org  
Lecturer, Discipline of General Practice, University of Adelaide  
www.adelaide.edu.au/directory/peter.mansfield  
peter.mansfield@adelaide.edu.au

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**Author:** ![b.futter](https://avatars.discourse-cdn.com/v4/letter/b/51bf81/32.png) [@b.futter](https://talk.edrugplus.org/u/b.futter)\
**Post date:** [November 26, 2007, 7:04am UTC](https://talk.edrugplus.org/t/e-drug-rational-versus-appropriate-medicines-use/28885/3 "2007-11-26T07:04:30Z")

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E-DRUG: Rational versus Appropriate Medicines Use (3)  
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A suggested intepretation of the differences between rational and appropriate. First point to bear in mind is that 'use' often refers to the prescriber, not just the patient.

Second is the question of Standards. When standard treatment guidelines are  
developed based on efficacy, and clinical data, there is an assumption about a standard rational patient (i.e. generic). This is the starting point.

However, people and circumstances differ. When these differences are taken into consideration, when making assumptions about patient behaviour, prescribing becomes appropriate. i.e. it becomes more cost effective.

cheers, Billy

Billy Futter  
Associate Professor  
Faculty of Pharmacy  
Rhodes University, Grahamstown, South Africa  
email B.Futter@ru.ac.za  
phone 046 603 8494  
fax 046 636 1205

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**Author:** ![pharmacomateriovigil](https://avatars.discourse-cdn.com/v4/letter/p/2acd7d/32.png) [@pharmacomateriovigil](https://talk.edrugplus.org/u/pharmacomateriovigil)\
**Post date:** [December 7, 2007, 12:40pm UTC](https://talk.edrugplus.org/t/e-drug-rational-versus-appropriate-medicines-use/28885/4 "2007-12-07T12:40:17Z")

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E-DRUG: Rational versus Appropriate Medicines Use (4)  
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Appropriate or Rational Use of medicines ?

Appropriate means correct or suitable, convenient, and correct means without mistake.

Does the prescription of the the right medicine to the right patient at the right dose is always without mistake ? I do not think so!

Rational means to do something according to the reason or to do something in one way able to reason (logical) or to persuade by a fair argument and more comprehensible mean. If you try to do something only with unbiased judgement, logically, rational is better than appropriate who is equivalent to correct, but in rational use all is not always correct. Consequently, keep rational use of medicines in your agenda.

A. Helali  
Clinical pharmacologist  
Director  
Centre National de Pharmacovigilance et de Matériovigilance  
BP. 247, Bab El Oued  
16009 Algiers  
Fone/fax : 213 21 36 36 71  
CNPM \<pharmacomateriovigilancedz@hotmail.com\>
