# \[e-drug\] Research paper on hidden drug costs (cont)

**URL:** <https://talk.edrugplus.org/t/e-drug-research-paper-on-hidden-drug-costs-cont/16099>\
**Category:** e-drug\
**Created:** [February 13, 2003, 4:27am UTC](https://talk.edrugplus.org/t/e-drug-research-paper-on-hidden-drug-costs-cont/16099 "2003-02-13T04:27:49Z")\
**Posts on this page:** 1\
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**Author:** ![owner-e-drug](https://avatars.discourse-cdn.com/v4/letter/o/bbce88/32.png) [@owner-e-drug](https://talk.edrugplus.org/u/owner-e-drug)\
**Post date:** [February 13, 2003, 4:27am UTC](https://talk.edrugplus.org/t/e-drug-research-paper-on-hidden-drug-costs-cont/16099/1 "2003-02-13T04:27:49Z")

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E-drug: Research paper on hidden drug costs (cont)  
---------------------------------------------

Dear E-druggers,

While I agree with the points made by Hilbrand Haak, I think there  
are additional factors to consider when reading Libby Levison's paper  
on "hidden costs".

Some of these may however be more reflective of my own environment  
than generally true of the wide range of countries that Libby  
surveyed (or of developing countries as a whole). South Africa might  
represent an atypical case - it is a middle income country with  
considerable local manufacturing capacity (also relevant perhaps to  
the current Para 6/Doha discussions?), and a distinct market served  
by both a for-profit private sector and a largely free (at point of  
care) public sector. Only 17% of the population have access to  
medical insurance (medical aid schemes), while most of the balance  
depend on the public sector (although the extent of out-of-pocket  
purchases remains poorly characterised). SA Pharmaceutical  
Manufacturing Association (PMA) projections for 2002 were that the  
public sector would account 23% of medicines sales (by value),  
private hospitals 13%, dispensing practitioners 12% and retail  
pharmacies 52% - worth in total about US$1.1billion.

My reason for quoting these figures is that the "hidden costs"  
operate to very different extents in the two major markets - while  
wholesale/retail mark-ups and VAT (as in Libby's Table 3) certainly  
contribute a lot in the private sector, they are also somewhat  
ameliorated by the practice of discounts, rebates and loyalty awards.  
The manufacturer's factor gate price is still the single largest  
component (see a chapter I did with Thulani Matsebula for the 2000 SA  
Health Review - at [http://www.hst.org.za/sahr/2000/chapter9.htm](http://www.hst.org.za/sahr/2000/chapter9.htm) - for  
details; we estimated the exit price as accounting for 60-69% of  
final prices to private sector purchasers). The public sector faces a  
totally different set of "hidden costs" - these are perhaps even more  
difficult to measure, as they should include issues such as losses  
due to shrinkage, expiry, irrational use, poor supplier performance  
and poor quantification. To further complicate matters, it could be  
argued that at least some of these also apply to the private sector.

SA is also not typical, in that it relies entirely on local  
procurement (including competitive bidding in the public sector), and  
also levies minimal import taxes, rendering import-related costs  
"hidden" in factory-gate prices.

While not all of Hilbrand's additional cost control mechanisms (to  
add to Table 4) are within the grasp of public policymakers (eg  
differential pricing can be seen as a choice made by manufacturers,  
cf. use of reference pricing as a government measure), he does add  
some useful pointers. Thulani and I listed the options open to  
government as:

\* Producer price control measures (direct price controls, reference  
pricing systems, equity pricing, generic policies)  
&nbsp;&nbsp;\* Distribution chain cost controls (mark-ups and fixed professional  
fees, value-added tax)  
&nbsp;&nbsp;\* Bulk purchase measures (tender and negotiation strategies,  
regional initiatives)  
&nbsp;&nbsp;\* International trade agreement relief measures (compulsory  
licensing, parallel importing)  
&nbsp;&nbsp;\* Demand side measures (rational drug use, co-payments).  
[note: we also listed equity pricing - is that really a govt choice?]

SA will also be worth watching in the near future, as it constitutes  
an advisory "Pricing Committee", prohibits bonusing, sampling and all  
forms of discount/incentive schemes, introduces parallel importation  
and allows for international tendering by the State procurement  
authorities. Regional procurement options have also been examined.

Overall, while these SA-specific twists and turns show how  
complicated the field is, they don't detract from a though-provoking  
paper. While Table 4 might be a bit "thin", the 9 identified policy  
and programming options remain valid. The last of those - introducing  
transparency - is one of the aims of the SA Medicines Amendment Act  
of 1997, expected to be brought into effect in April 2003. Achieving  
that goal is not going to be easy.

regards  
Andy

Andy Gray  
Senior Lecturer  
Department of Experimental and Clinical Pharmacology  
Nelson R Mandela School of Medicine  
University of Natal  
andy@healthlink.org.za  
PBag 7 Congella 4013  
South Africa  
Tel: 27-31-2604334/4298 Fax: 27-31-2604338  
"Andy Gray" \<andy@gray.za.net\>  
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