# E-DRUG: Reviews of antibiotic use

**URL:** <https://talk.edrugplus.org/t/e-drug-reviews-of-antibiotic-use/614>\
**Category:** e-drug\
**Created:** [April 10, 1997, 3:25pm UTC](https://talk.edrugplus.org/t/e-drug-reviews-of-antibiotic-use/614 "1997-04-10T15:25:55Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![drossdeg](https://avatars.discourse-cdn.com/v4/letter/d/73ab20/32.png) [@drossdeg](https://talk.edrugplus.org/u/drossdeg)\
**Post date:** [April 10, 1997, 3:25pm UTC](https://talk.edrugplus.org/t/e-drug-reviews-of-antibiotic-use/614/1 "1997-04-10T15:25:55Z")

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Re: antibiotic (mis)use  
-----------------------

Dear David.

Unnecessary prescribing of antibiotics is clearly a major problem in all  
countries, resulting in wasted resources and contributing to the development  
of antibiotic resistance. Our recent review of evidence from developing  
countries completed for the International Conference on Improving Use of  
Medicines has shown that strategies like (1) focused, problem-oriented  
training on treatment for diarrhea and respiratory infections, (2)  
supervision or self-monitoring using simple indicators, and (3) peer  
group-oriented guideline development can all reduce unnecessary use.

However, less is not always better. I suggest that from a developing  
country viewpoint, you do not want to limit your attention to problems of  
overuse. Failure to prescribe antibiotics correctly when they are needed,  
and failure to obtain and complete a full course of therapy, may be much  
more significant in their immediate clinical effects. For example, studies  
in a number of countries in Africa and Asia focused on improved community  
case management for pneumonia (better prescribing of recommended therapies)  
have demonstrated dramatic reductions in child mortality.

Dennis Ross-Degnan  
Drug Policy Research Group  
Dept. of Ambulatory Care & Prevention  
Harvard Medical School Tel: +1 617-421-2631  
126 Brookline Avenue, Suite 200 Fax: +1 617-859-8112  
Boston, MA 02215 USA E:mail: drossdeg@warren.med.harvard.edu

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