# \[e-drug\] Treatment of Malaria (cont) **URL:** \ **Category:** e-drug\ **Created:** [January 16, 2001, 11:04pm UTC](https://talk.edrugplus.org/t/e-drug-treatment-of-malaria-cont/10078 "2001-01-16T23:04:10Z")\ **Posts on this page:** 1\ **Page:** 1
**Author:** ![Dr\_S\_Toovey](https://avatars.discourse-cdn.com/v4/letter/d/71e660/32.png) [@Dr\_S\_Toovey](https://talk.edrugplus.org/u/Dr_S_Toovey)\ **Post date:** [January 16, 2001, 11:04pm UTC](https://talk.edrugplus.org/t/e-drug-treatment-of-malaria-cont/10078/1 "2001-01-16T23:04:10Z")
E-drug: Treatment of Malaria (cont) --------------------------------------------- There is work from the Bangkok children's hospital showing that mefloquine can be followed by quinine. Further recent work by French researchers working in Africa has shown that mefloquine does not cause the sort of QT prolongation that halofantrine does. This corroborates the work from Bangkok, removing the theoretical contra-indication to following mefloquine with quinine. Following mefloquine with chloroquine would not make sense, as a parasite resistant to mefloquine would most likely not be susceptible to chloroquine. The prophylaxis may not have failed because of parasite resistance, but it is probably safer clinically to assume so. Dr Stephen Toovey American Society of Tropical Medicine and Hygiene certified in Clinical Tropical Medicine and Travellers' Health, Aviation Medical Examiner toovey@travelclinic.co.za [http://www.travelclinic.co.za](http://www.travelclinic.co.za) [http://www.malaria.co.za](http://www.malaria.co.za) P O Box 786692 Sandton 2146 South Africa Fax: +27-11-883-6152 -- Send mail for the `E-Drug' conference to `e-drug@usa.healthnet.org'. Mail administrative requests to `majordomo@usa.healthnet.org'. For additional assistance, send mail to: `owner-e-drug@usa.healthnet.org'.