# \[e-med\] Field Testing d'un pack antirétroviral de prévention mère-enfant

**URL:** <https://talk.edrugplus.org/t/e-med-field-testing-dun-pack-antiretroviral-de-prevention-mere-enfant/33014>\
**Category:** e-med\
**Created:** [December 30, 2009, 2:10pm UTC](https://talk.edrugplus.org/t/e-med-field-testing-dun-pack-antiretroviral-de-prevention-mere-enfant/33014 "2009-12-30T14:10:58Z")\
**Posts on this page:** 1\
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**Author:** ![Tifenn\_Humbert](https://avatars.discourse-cdn.com/v4/letter/t/7bcc69/32.png) [@Tifenn\_Humbert](https://talk.edrugplus.org/u/Tifenn_Humbert)\
**Post date:** [December 30, 2009, 2:10pm UTC](https://talk.edrugplus.org/t/e-med-field-testing-dun-pack-antiretroviral-de-prevention-mere-enfant/33014/1 "2009-12-30T14:10:58Z")

</div>

Chers Collegues,

En raison des fetes de fin d'année, UNICEF a decidé de prolonger le delais  
de submission de la demande d'expression d'interet ci-dessous jusqu'au 15  
Janvier 2010.

----- Forwarded by Tifenn Humbert/DAN/HQ/UNICEF on 30/12/2009 15:06 -----

Tifenn Humbert/DAN/HQ/UNICEF  
17/12/2009 17:21

To  
e-med@healthnet.org  
cc

Subject  
EXPRESSION OF INTEREST (EOI) - Reference EOI-MBP Field Testing Phase  
2(UNICEF)

Dans le cadre du developpement du Mother-Baby Pack (MBP) pour la PTME  
(Prevention de la Transmission de la Mere a l'Enfant du VIH), l'UNICEF  
diffuse la demande d'expression d'interet suivante:

UNITED NATIONS CHILDREN'S FUND (UNICEF)

EXPRESSION OF INTEREST (EOI) - Reference EOI-MBP Field Testing

Date of the EOI: 18 December 2009  
Closing Date of the EOI: 8 January 2010  
Address EOI by e-mail to: Ms. Tifenn Humbert at thumbert@unicef.org

TERMS OF REFERENCE  
UNICEF Supply Division welcomes eligible institutions to submit an  
expression of interest to undertake field testings of the Mother-Baby  
Pack, an innovative simple, user-friendly and affordable packaged  
mechanism to deliver prophylactic antiretroviral (ARV) regimens for the  
prevention of mother-to-child transmission (PMTCT) of HIV.

1. Background and Project Summary

In 2008, 45% of pregnant women living with HIV in low-and middle-income  
countries received antiretroviral drugs to prevent HIV transmission to  
their infants, including antiretroviral therapy for their own health  
Toward Universal Access. Scaling up HIV services for women and children in  
the health sector. Progress report 2009.. Indeed, PMTCT coverage is still  
quite low globally and national programmes are facing various challenges  
translating the WHO guidelines PMTCT Antiretroviral medicines for treating  
pregnant women and preventing HIV infection in infants: toward universal  
access  
[http://www.who.int/hiv/pub/mtct/pmtct/en/](http://www.who.int/hiv/pub/mtct/pmtct/en/) into actions. This is mainly  
attributable to weak health systems, frequent stockouts of medicines,  
social and cultural obstacles, and many PMTCT candidates are missed or do  
not get the full complement of medicines they need.

UNICEF in collaboration with WHO and global partners supporting PMTCT and  
paediatric HIV care, support and treatment is developing an innovative  
simple, user-friendly and affordable package mechanism to deliver PMTCT  
prophylactic medications, the Mother-Baby Pack (MBP). The MBP contains  
medicines for prophylaxis, ARVs and Cotrimoxazole, for the mother and for  
the infant in line with WHO PMTCT Guidelines (2006) and new  
recommendations from November 2009.

2. Purpose of MBP

The MBP is an innovative product aimed to facilitate the scale-up and  
increased uptake of more efficacious ARV prophylactic regimens for PMTCT  
(combination of Zidovudine and Single-dose Nevirapine) and Cotrimoxazole  
prophylaxis in resource-limited settings in line with 2006 WHO Treatment  
guidelines and new WHO recommendations from November 2009. The MBP also  
intends to help streamline the procurement and supply management of PMTCT  
prophylactic medicines.

The initiative takes into consideration limited capacities of health care  
systems (institutional and human), operational management including  
tracking and follow-up mechanisms for a continuum of care, as well as the  
health seeking behaviours of clients.

3. Project Requirements

The full pack is intended to be distributed within ANC clinics to  
HIV-positive pregnant woman, ideally at the first ANC visit from week 14  
of pregnancy or at the earliest opportunity thereafter. Moreover, some  
pregnant women may come later (up to 40 weeks of pregnancy). The MBP will  
be also distributed through maternity/delivery facilities to target women  
presenting for the first time to the health facility at labour and also  
for those seen during pregnancy who received a MBP but will not bring  
their pack at the time of delivery.

The MBP is designed to be used both within and outside the clinical  
setting. It is intended to be user-friendly, manageable, and  
water-resistant. It includes the principal PMTCT commodities in their  
basic unit packaging to allow for flexibility of dispensing and  
administration to patient.

The objective of the proposed assignment for which UNICEF invites EOIs is  
to facilitate the field testing of the Mother-Baby Pack inclusive of its  
contents and packaging in the context of PMTCT Programmes, and to provide  
performance (effectiveness) and management (efficiency) feedback to the  
Mother Baby Pack Technical Working Group with the intention to contribute  
to strengthening the effectiveness of the pack itself and its potential  
impact on scale-up and increased uptake of more efficacious ARV  
prophylactic regimens for PMTCT.

Under the overall guidance of UNICEF and as informed by the Mother Baby  
Pack Technical Working Group, the selected institution is expected to work  
together with the stakeholders via the UNICEF Project Manager in  
field-testing the prototype.

The field testing of the MBP will be conducted in selected African  
countries. These field trials are important as it will assess the  
introduction of the full MBP (inclusive of its contents) and will measure  
its impact on PMTCT uptake. During this process, issues related to stigma,  
adherence, supply chain and programmatic issues will be taken into  
consideration.

Following the Expression of Interest, UNICEF expects to issue Requests for  
Proposals (RFP) in the first quarter of 2010 to all qualified entities who  
had submitted EOIs and to other interested institutions.

SUBMISSION OF EXPRESSION OF INTEREST (EOI)  
Interested institutions are encouraged to complete and submit below EOI  
form.  
EOIs should be sent to Ms. Tifenn Humbert, e-mail: thumbert@unicef.org,  
not later than 8th January 2010. Please quote ?EOI ? MBP Field Testing as  
subject in your correspondence.  
This EOI does not constitute a solicitation. We do not require bids or  
proposals at this stage; we merely seek your expression of interest in  
participating in the tender.  
A response to this Request for Expression of Interest does not  
automatically ensure that you will be selected to participate in the  
tender.  
UNICEF reserves the right to change or cancel the requirement at any time  
during the EOI and/or solicitation process. UNICEF also reserves the right  
to require compliance with additional conditions as and when issuing the  
final tender document.  
If you have any additional question about this EOI, please contact Ms.  
Tifenn Humbert, e-mail: thumbert@unicef.org.

EXPRESSION OF INTEREST FORM (EOI form) - Reference EOI-MBP Field Testing

[Please check the box when appropriate]

GENERAL INFORMATION

Full company name:

Manufacturer:  
Trader:  
Service provider:  
Address:

Country:

Contact Person:

E-mail address:

Tel:

Fax:

Alternative Contact person:

E-mail address:

INTEREST IN SUPPLYING THE FOLLOWING SERVICE[S]

Yes  
No  
Quantitative & qualitative research on HIV/AIDS scale-up efforts.

Training of health service providers.

Survey and research analysis.

Procurement and supply chain management.

QMS

[Specify QMS required]

If others, please specify

ADDITIONAL INFORMATION

Company established in? (year)

Registration as legal entity in?(country)

Years of experience providing similar goods/service(s)

Registration with UNGM  
www.ungm.org

If so, registration number:

On completion, return this form to UNICEF by email to Tifenn Humbert (  
thumbert@unicef.org) on or before 8 January 2010.
