# RE: E-DRUG: alternatives for chloroform?

**URL:** <https://talk.edrugplus.org/t/re-e-drug-alternatives-for-chloroform/5812>\
**Category:** e-drug\
**Created:** [August 19, 1999, 7:08am UTC](https://talk.edrugplus.org/t/re-e-drug-alternatives-for-chloroform/5812 "1999-08-19T07:08:17Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![karina\_y\_adrian](https://avatars.discourse-cdn.com/v4/letter/k/e19adc/32.png) [@karina\_y\_adrian](https://talk.edrugplus.org/u/karina_y_adrian)\
**Post date:** [August 19, 1999, 7:08am UTC](https://talk.edrugplus.org/t/re-e-drug-alternatives-for-chloroform/5812/1 "1999-08-19T07:08:17Z")

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E-DRUG: alternatives for chloroform?  
------------------------------------

> Please could any one suggest alternative formulations which do not contain  
> chloroform as a preservative, and state the reference for the formula, for  
> the following:

For mist morphine you should try methylparaben 0.1%  
For paracetamol syrup: methylparaben 0.1% and propylparaben 0.03%

I send you a list of ordinary preservatives

Preservatives Usual Concentration pH  
alquilic esters of  
p-hidroxybenzoic acid 0.010-0.20% 3.4-7.5  
acid benzoic and salts 0.10-0.30 % \< 4.5  
ethanol 10-15% doesn't matter  
bencilic alcohol 1-2% doesn't matter

Seek for incompatibilities!

Karina Szydlovski  
Pharmacist  
Buenos Aires  
Argentina  
e-mail kariadri@cvtci.com.ar

[Thanks, Karina! WB]

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