E-DRUG: Asthma medication - Ketotifen (2)
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Ketotifen is approved in Canada for asthma. I would regard it as
definitely a second-line drug for children who cannot tolerate/use
inhaled steroids.
Joel Lexchin MD
121 Walmer Rd.
Toronto, Ontario
CANADA M5R 2X8
Phone: (416)-964-7186
Fax: (416)-923-9515
e mail: joel.lexchin@utoronto.ca
E-DRUG: Ketotifen in asthma (3)
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Ketotifen is only effective in obviously allergic forms of asthma, eg
aspirin-induced bronchospasm, and then its action is no different
from that of any "ordinary" antihistaminic like clemastine. For
references see Dollery Vol.II-K28.
Anyhow, antihistamines have no longer a role of any importance in the
modern treatment of asthma. I would like to refer to the official
American DHHS guidelines (Expert Panel Report of the National Asthma
Education Program - US Dept. of Health & Human Services, Publ.
91-3042A, 1991).
Leo Offerhaus MD PhD
Koedijklaan 1a 1406 KW Bussum The Netherlands
Tel 0031-35-6923288 Fax 0031-35-6923290
E-mail LO@EURONET.NL, CompuServe 71530,15
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