Dear E-druggers,
The March 1997 issue of the Journal of Pediatrics has published
results of a randomized, double-blind, placebo-controlled trial to
determine if antihistamine-decongestant combination (ADC) is effective
in relieving symptoms of the common cold in children (Clemens CJ,
Taylor JA, Almquist JR, Quinn HC, Mehta A, Naylor GS. Is an
antihistamine-decongestant combination effective in temporarily
relieving symptoms of the common cold in preschool children?
1997;130:463-6).
The researchers from the Department of Pediatrics at the University of
Washington, Seattle concluded that the ADC was equivalent to placebo
in providing temporary relief of URI [upper respiratory tract
infection] symptoms in preschool children. However, the ADC did have
significantly greater sedative effects than did placebo.
Thought this maybe of interest to some E-Drug subscribers.
Syed Rizwanuddin Ahmad
United States Pharmacopeial Convention, Inc.
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