E-drug: Contents of Prescrire International, August 2001
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Prescrire international is the English language edition of la revue
Prescrire It contains comprehensive evaluations of new drugs and
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Contents of Prescrire International
August 2001 Volume 10, No 54
EDITORIAL
Drugs agencies must be more open
NEW PRODUCTS
Scopolamine (new preparations)
Injectable form relieves death rattle
Trastuzumab (new preparation)
Too many unknowns for use in metastatic breast cancer
Filgrastim (new indication)
No proven value in AIDS-associated neutropenia
Exemestane (new preparation)
No advantage over existing aromatase inhibitors
Mitoxantrone (new indication)
Poor assessment of analgesic effects in advanced prostate cancer
Disodium valproate (new preparation)
Helpful for acute mania after lithium failure or intolerance
ADVERSE EFFECTS
Nicotine substitutes and pregnancy
Unknown efficacy and safety
Ischaemic colitis on pseudoephedrine
Beware non prescription products
Extrapyramidal effects of SSRI antidepressants
All SSRIs are involved
Phenobarbital for mild sedation: market withdrawal
Long awaited
Stroke and phenylpropanolamine (continued)
Mild symptoms do not call for risky preparations
REVIEWS
Calcium channel blockers
Third-line antihypertensives
Severe anaphylaxis outside the hospital setting
Inject adrenaline intramuscularly
SHORTCUTS
. Diabetes: preventing severe foot lesions . Quinupristin +
dalfopristin . Interferon alfa-2 and melanoma . Desogestrel .
Ethinylestradiol 15 mg + gestodene 60 mg
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