E-DRUG: JAMA on bias in reports on drug benefits
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[copied from PHARM-POLICY with thanks; WB]
[Full JAMA story:
http://jama.ama-assn.org/issues/v282n18/full/jsc90228.html
For printing, use the PDF file:
http://jama.ama-assn.org/issues/v282n18/pdf/jsc90228.pdf
WB]
Problems in the Design and Reporting of Trials of Antifungal Agents
Encountered During Meta-analysis Helle Krogh Johansen, MD, DMSc ;
Peter C. G�tzsche, MD, DMSc
The popular write-up in NYTimes:
http://www.nytimes.com/library/national/science/health/111099hth-drugs-effect.html
Medical Journal Cites Misleading Drug Research
Nov 10, 199 By DENISE GRADY
Reports of research on drugs tend to exaggerate the drugs' benefits, making them sound better than they really are, according to an article and editorial being published
Wednesday in The Journal of the American Medical Association.
The exaggeration occurs for several reasons: positive results tend to be published more often than negative ones, researchers sometimes publish the same study more than
once and some poorly designed studies slip through the safety net of journal editors and expert reviewers who should screen them out.
[snip]
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James Love / Director, Consumer Project on Technology
http://www.cptech.org / love@cptech.org
P.O. Box 19367, Washington, DC 20036
voice 202.387.8030 / fax 202.234.5176
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