E-DRUG: Low Molecular Weight Heparins (cont)
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I have a meta-analysis comparing LMWH with unfractionated heparin that
was published in the Annals of Internal Medicine 1999;130:800-809.
The conclusions werethat the type of LMWH studied influenced the risk of
bleeding although no single preparation was found to be better or worse
than the others. Studies that used dalteparin, tinzaparin, nadroparin
favoured LMW heparins whereas studies that used enoxaparin and reviparin
favoured unfractionated heparin. The treatment benefit was
statistically significant only for tinzaparin.
Joel Lexchin
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Joel Lexchin MD
121 Walmer Rd.
Toronto, Ontario
CANADA M5R 2X8
Phone: +416-964-7186
Fax: +416-923-9515
e mail: joel.lexchin@utoronto.ca
[Thanks, Joel! Is the Annals of Int Med somewhere on the Internet? WB]
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