E-DRUG: Prescrire Independent Drug and Healthcare Newsletter October 2020
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Newsletter, October 2020
Independant information by and for healthcare professionals
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In Prescrire's Spotlight this month:
The 2020 "Prescrire Prize" is awarded in Paris to 3 noteworthy books about health and healthcare
The recipients of the 2020 "Prescrire Prize" book awards were announced on 1 October 2020. The prize is awarded to works of particular interest to the general public and/or healthcare professionals.
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FEATURED REVIEW
Apixaban, edoxaban, rivaroxaban: situations with a high risk of bleeding or thrombosis
When using xabans, it is essential to take into account the situations that increase the risk of bleeding or thrombosis, and to monitor the patient for any change in these risks, such as new comorbidities, new drugs, or discontinued drugs.
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FREE DOWNLOAD
In the October issue of Prescrire International: A public awareness campaign which mainly benefits companies
The pharmaceutical company Abbvie, which markets adalimumab (Humira°), has jointly funded a public awareness campaign produced by the patient organisation France Psoriasis. Objective: marketing. Full text available for free download.
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NEWS UPDATE
Covid-19 patients who are not hospitalised: anticoagulation is rarely justified
The risk of thromboembolism in patients with a mild to moderate form of covid-19 is unclear and probably varies greatly between patients. Is anticoagulation justified to prevent deep vein thrombosis in patients with covid-19 who are not hospitalised?
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NEWS UPDATE
Proton pump inhibitors: increased risk of severe covid-19
Proton pump inhibitors (PPIs) are known to increase the risk of various infections, including pneumonia and pseudomembranous colitis. What about covid-19 infection? A recent study yields some useful information.
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EDITORIAL
Hydroxychloroquine: the situation is critical
According to the methodological principles of clinical evaluation, comparative trials provide the most reliable evidence when evaluating treatments. The lowest-level evidence comes from expert opinions, case series, other observational studies and empiricism. This is still true in 2020 - and also in covid-19.
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REVIEWS
Pinworm infection: easy to detect and easy to treat
Anal itching at night is highly suggestive of pinworm infection, an intestinal parasitic infection that is very common in children. Several drugs, none of which have serious adverse effects, eradicate the parasites, after two doses, given two weeks apart.
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ADVERSE EFFECTS
Gentian violet used when breastfeeding: irritant and carcinogenic
Gentian violet has no place in the treatment of nipple thrush while breastfeeding, nor of oral thrush in the newborn baby.
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COMING SOON
Enjoy these features, and more, in our upcoming issues
Atezolizumab as an adjunct to cytotoxic drugs in lung cancer * Dapagliflozin in type 1 diabetes: serious harms * Valproic acid during pregnancy: effects on the third generation? * Doxylamine during pregnancy * Should blood pressure-lowering drugs be taken at bedtime?...
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