E-drug: Prices of antimalarial combinations (cont'd)
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I have copied below, on a fair use basis, the latest Cochrane review
I could find. Perhaps somebody has a later review. The conclusion
seems to be that the toxicity issue is far from settled, with the
reviewers calling for continued monitoring.
I also copied an abstract, on a fair usage basis, that illustrates the
problems associated with both Fansidar and Amodiaquine in East
Africa.
I believe it would be a surprise if resistance were not found to be a
problem in Zambia, and that it would not be prudent to introduce
either Fansidar (or generic equivalent) or amodiaquine without
documenting that resistance and toxicity were not problems in
Zambia.
Zambians deserve better than the introduction of old, possibly
toxic, and perhaps ineffective drugs.
Dr Stephen Toovey
SAA-Netcare Travel Clinics
P O Box 786692
Sandton 2146, South Africa
Fax: +27-11-883-6152
e-mail: toovey@travelclinic.co.za
http://www.travelclinic.co.za
http://www.malaria.co.za