E-drug: rectal formulation of chloralhydrate (2)
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As an emergency physician I would not recommend the use of rectal (or oral)
chloralhydrate. It has irregular absorption resulting in a delayed onset
(about 60 min.), variable efficacy and prolonged sedation. For pediatric
sedation I would recommend one of the following:
Midazolam: 0.5-0.7 mg/kg orally (mix in apple juice with sweetner)
0.05 mg/kg i.v.
Ketamine: 3-4 mg/kg i.m.
0.25-0.5 mg/kg i.v., titrated to effect
6-10 mg/kg orally
Joel
Joel Lexchin MD
121 Walmer Rd.
Toronto, Ontario
CANADA M5R 2X8
Phone: (416)-964-7186
Fax: (416)-923-9515
---technical note from the moderator:
Can people please include their E-mail address in the signature?
That would help when people react to messages.
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