E-DRUG: Russian Drug INTERCORDIN

Thanks to all the E Druggers who helped with the identification of
INTERCORDIN. Here is a summary of the information sent to me .

INTERCORDIN

GENERIC NAME: carbocromen or carbocromenum or chromonar
                                   hydrochloride
OTHER
PROPRIETARYS: Intensain, Cardiocap, Intencordin, Antiangor,
NAMES Intensacrom

USES: It is listed as a vasodilator which has
                                been used in ischaemic heart disease

DOSE: Varying dosage regimens have been used
                                but in general it is within the range
                                of 150 to 450mg daily by mouth

EFFICACY: Information is limited and its efficacy appears to
be poor. It has been withdrawn from many European markets (if it
ever got marketing approval). Substitute agents appear to be either
an organic nitrate or nifedipine.

REFERENCES
1. Martindale Extra Pharmacopoea 31st Edition p841.3
2.Franchi F et al Evaluation of Electrophysiological effects of
antianginal Drugs Reprint 1981; 3(1): 17-27
3.Franch F Haemodynamic Effects of carbochromen Curr Ther Res 1980;
28(2): 243-252

Thankyou for all your help with identification

Janet McNeece
Senior Pharmacist, Drug Information centre,
Royal Adelaide Hospital
South Australia, SA5063

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