E-DRUG: WHO launches new ORS
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[WHO launches a new ORS formula... But what is the new formula? It was not
proposed to the recent EDL Expert Committee. WB]
Press Release WHO/35
8 May 2002
NEW FORMULA FOR ORAL REHYDRATION SALTS WILL SAVE MILLIONS OF LIVES
Number of deaths and severity of illness will be reduced
Geneva and New York - The new formula Oral Rehydration Salts (ORS),
released by the World Health Organization (WHO) today, will save millions
of lives and reduce the severity of illness of those suffering from acute
diarrhea. ORS is a sodium and glucose solution that is widely used to treat
children with acute diarrhea, a serious killer of children under five
worldwide. The new formula ORS will reduce the severity of diarrhea and
vomiting, the number of hospitalizations, the need for costly intravenous
(IV) fluid treatment and the length of illness.
The use of ORS is responsible for saving the lives of millions of children
worldwide. This inexpensive and readily available intervention reduces
death and suffering from dehydration caused by diarrhea. Since WHO adopted
ORS in 1978 as its primary tool to fight diarrhea, the mortality rate for
children suffering from acute diarrhea has fallen from 5 million to 1.3
million deaths annually.
The new improved formula is the result of extensive research sponsored by
WHO's Department of Child and Adolescent Health and Development and
supported by the U.S Agency for International Development (USAID). The
latest study was conducted in five developing countries among children from
one month to two years old with acute diarrhea and dehydration.
The study's findings suggest that using the low-sodium, low-glucose ORS
formulation reduces the need for intravenous fluids by 33 percent. The
effect of this reduction could result in fewer children requiring
hospitalization, fewer secondary infections, a diminished need to handle
blood with its potentially dangerous consequences, and lower health care
costs.
"Oral Rehydration Therapy is one of the great public health success stories
of our time," according to Dr Gro Harlem Brundtland, Director-General of
WHO. "Reducing childhood deaths from diarrhea by half in ten years is a
notable success but, despite this progress, diarrhea remains a major cause
of death. This week at the UN General Assembly Special Session on Children
governments will endorse a new goal to reduce deaths from diarrhea by a
further 50 percent by 2010."
Oral Rehydration Therapy was first researched in the 1940s but it was
twenty years later before the idea was developed by research institutions
in Bangladesh and India for the management of severe cholera. Then
conventional wisdom said only health professionals could mix and administer
the solution and that its use was limited to hospitals. The use of ORS
during the 1971 war between India and Pakistan provided convincing evidence
that ORS could be given by non-medical personnel, volunteers and family
members.
The war provoked a public health emergency in the unsanitary, overcrowded
and primitive border camps set up to house those fleeing the violence. The
camps quickly became breeding grounds for diseases, especially cholera.
With cholera spreading rapidly and death rates rising, the head of a
medical centre in one of the camps instructed his staff to distribute ORS
that was stored in steel drums around the camp. The distribution, like the
solution, was simple but effective. The ORS solution administered by family
members and others dramatically reduced the death rates from diarrhea.
In the refugee camps where ORS was being used the death rate was only 3
percent compared to between 20 and 30 percent in those camps using only
intravenous fluid therapy. But, still the medical community held out -
sceptical that such a devastating problem could have such a simple
solution.
The dramatic improvement in home management of diarrhea through ORS use
took place between 1990 and 1995, saving about 1 million children annually.
In 1990, oral rehydration salts were used in approximately one-third of
diarrhea cases, and by mid-decade the average was 85 per cent among 33
reporting countries that account for almost half of the world's under-five
population.
"To reach the 2010 goal we need to expand the use of ORS dramatically. To
do this the role of parents, volunteer care givers and health workers is
going to be vital. Having access to packets of oral rehydration salts when
you need them is also very important to scaling-up. Ideally, all families
should have packets of ORS in the home ready to be mixed as soon as it is
needed. Using ORS packets should become routine at the first signs of
diarrhea to avoid the risk of parents waiting too long before rehydrating
the child. If we can achieve this, the 2010 goals should be well within our
reach," says Dr Tomris Turmen, Executive Director, Family and Community
Health at WHO .
Use of the new formula ORS will begin later this year in India.
For more information, contact Chris Powell, Information Officer, Family and
Community Health, WHO, Geneva. Tel. (+41 22) 791 2888; mobile (+41) 79 217
3425; E-mail: powellc@who.int.
All WHO Press Releases, Fact Sheets and Features as well as other
information on this subject can be obtained on Internet on the WHO home
page http://www.who.int/
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