E-MED: M�dicaments pour le traitement des infections bact�riennes
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WHO Model Prescribing Information
Drugs used in Bacterial Infections
http://www.who.int/medicines/library/bacterial_model_pres/bacterial_content.
shtml
Preface 1
Introduction 3
Resistance to antimicrobials 3
Role of laboratories in antimicrobial susceptibility testing and reporting
of surveillance data 5
General principles of antimicrobial prescribing 7
Choice of antimicrobial and options for treatment 9
Upper respiratory tract infections 14
Acute pharyngitis 14
Nasopharyngitis, rhinitis and common cold 15
Otitis media 15
Acute mastoiditis 17
Acute sinusitis 17
Croup (laryngotracheobronchitis) 18
Epiglottitis 18
Diphtheria 19
Lower respiratory tract Infections 20
Bronchitis 20
Chronic recurrent cough 21
Pneumonia 21
Other respiratory tract Infections 31
Pertussis (whooping cough) 31
Ornithosis 31
Melioidosis 31
Perioral and dental Infections 33
Gingival infections and periodontitis 33
Tooth abscesses and suppurative odontogenic infections 33
Acute cervical adenitis 34
Gastrointestinal tract Infections 35
Diarrhoeal disease 35
Acute enteric infections 38
Non-diarrhoea) gastrointestinal infections 41
Urinary tract infections 43
Urinary tract infections in women 43
Urinary tract infections in men 44
Urinary tract infections in children 44
Acute pyelonephritis 45
Prostatitis 45
Skin and soft tissue Infections 47
Localized purulent skin lesions 47
Impetigo 47
Cellulitis and erysipelas 48
Streptococcal necrotizing fasciitis 49
Gangrene 49
Pyomyositis 50
Contaminated soft tissue injuries 51
Human and animal bites and clenched-fist injuries 51
Bone and joint Infections 53
Osteomyelitis 53
Septic arthritis 57
Sexually transmitted diseases 61
Gonorrhoea 61
Lymphogranuloma venereum 62
Other chlamydial infections 63
Vaginitis 64
Pelvic inflammatory disease 64
Syphilis 66
Chancroid 67
Granuloma inguinale 68
Cardiovascular Infections 69
Infective endocarditis 69
Prosthetic valve endocarditis 73
Pericarditis and myocarditis 73
Rheumatic fever 73
Central nervous system Infections 75
Meningitis 75
Brain abscess 80
Miscellaneous Infections 81
Lyme disease 81
Relapsing fever 81
Leptospirosis 82
Brucellosis 82
Tularaemia 83
Anthrax 83
Plague 84
Rickettsial infections 85
Q fever 85
Septicaemia 86
Initial empirical therapy 86
Prophylaxis 88
Surgical prophylaxis 88
Non-surgical prophylaxis 89
Drugs 92
amoxicillin 92
amoxicillin + clavulanic acid 94
ampicillin 96
benzylpenicillin 99
benzathine benzylpenicillin 103
procaine benzylpenicillin 104
cefalexin 106
cefazolin 108
cefotaxime 110
ceftazidime 112
ceftriaxone 113
cefuroxime 117
chloramphenicol 117
ciprofloxacin 121
clindamycin 124
cloxacillin 126
doxycycline 131
erythromycin 134
gentamicin 137
imipenem + cilastatin 142
metronidazole 142
nalidixic acid 146
nitrofurantoin 147
nystatin 147
phenoxymethyl peniciIIin 148
rifampicin 149
spectinomycin 152
streptomycin 153
sulfadiazine 154
sulfamethoxazole + trimethoprim 156
tetracycline 159
tinidazole 161
trimethoprim 162
vancomycin 163
Index 166
World Health Organization
Geneva
2001
WHO Library Cataloguing-in-Publication Data
WHO model prescribing information : drugs used in bacterial infections.
1.Anti-infective agents, Fluoroquinolone - administration and dosage
2.Antibiotics, Lectern - administration and dosage
3.Vancomycin - administration and dosage 4.Drug resistance, Microbial
5.Essential drugs
6.Prescriptions, Drug- standards I.Title: Drugs used in bacterial infections
ISBN 92 4 140107 9 (NLM classification: OV 250)
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