[afro-nets] Mosquito/Malaria Control (24)

Mosquito/Malaria Control (24)
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Dear all,

It's really interesting regarding the ongoing discussion on ma-
laria control in Africa.

The epidemic has been in Africa for many decades but looks like
we still don't know what really works in terms of prevention.

Hundreds of thousands of researches have been carried out on ma-
laria prevention, still different thought of what works bugs
most of us.

We know ITN works for sure. Accessibility and proper use pulls
back the desired effectiveness of ITNs in most places.

Anopheles mosquito, the guy behind all these have been shown to
actively bite towards midnight.

This means that, though our sisters and children go to bed late,
they can be well protected during these "effective biting hours"
of the mosquito. However, this does not exclude the danger of
some bites taking place before going to bed.

But even if ITNs were available and well used, who knows for
sure what is going to be the long term impact?

There has been a threat of "rebound epidemic" after a long term
protection from the exposure for partial immuno-stimulation.

Most people will be entirely non-immune, and the mosquitoes will
still be there and probably carrying more resistant species.

This warrants the need to combine both, burden reduction with
ITN as well as mosquito eradication for future impact of the
non-immune society that we are creating with the ITN.

Elia John
mailto:eliajelia@yahoo.co.uk

Mosquito/Malaria Control (25)
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Indeed Elia,

eradication of mosquitoes would work much better!

Lukesia Rugeiyamu
mailto:lukesiar@yahoo.com

Mosquito/Malaria Control (26)
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Hi Elia,

You almost have it right. The proper use of bednets in malaria
control call for their use to isolate a person suffering from an
active malaria attack from the mosquito. This is especially true
after some of the recent research showing that the malaria para-
site actually makes the victim more palatable to the mosquito.

The attempts to use bednets as the first, and really only, line
of defense is a waste of time at best and criminal at it's
worst. There are too many human variables associated with the
bednet issue.

Also, I would like to see some solid data on the feeding habits
of the anopheles showing that they don't feed outside and that
they will wait for people to go to bed before biting. So far
I've not seen anything of this nature. This malaria problem
should fall under the general heading of "Human Rights". There
is no greater right than that to life.

Cheers,

Bill Nesler
mailto:sdbc@hur.midco.net

Mosquito/Malaria Control (27)
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Bill,

I see a lot of passion in your arguments! Have you been a victim
of malaria?!

Let us spread this concept more concertedly around the globe and
try to change the mindset.

Kris Dev
mailto:krisdev@gmail.com

Mosquito/Malaria Control (28)
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Hehehe, Kris that was a good one.....!

However back to the main issue I still insist like some others
have already said that there is need of a multi pronged approach
to the malaria problem in Africa, bednets, larvicidals, spraying
and whatever; but lets start with protecting the most vulnerable
groups which is the women and children... and these ones most
definitely get bit at night... lets not get sidetracked into
discussing when and how the mosquitoes biting habits may change.
I have seen so many kids die from malaria who could have been
saved by availability of effective affordable medication and
even a few preventive measures.

In Africa, where I live, I really wonder which area you would
spray... I really wonder! Maybe Bill could give us an idea of
where and how much insecticide would be needed and which compa-
nies would benefit from the efforts.

" As for me and my house"... to quote from Joshua in the Bible I
will stick to tried and tested methods, avoiding bites with ap-
propriate clothing and repellents, sleeping under a treated net
and having timely treatment of any of the parasites that get
through this barricade with EFFECTIVE antimalarials.

I have witnessed improvement in the quality of peoples live
while using these three methods and I have seen reduced morbid-
ity and mortality in families using nets with the help of these
observations I have no problem choosing what I will use... I
will wait till the population becomes majority urban before I
start advocating for spraying as the main means of control of
malaria

Dr Isaac Michael Kigozi
National Drug Authority, Uganda
Plot 46-48 Lumumba Avenue
P.O.Box 23096
Tel +256-41-255-665
Mobile +256-77-982-411
mailto:kigoziisaac76@yahoo.co.uk
mailto:pistollero76ug@yahoo.co.uk
mailto:kigoziisaac@hotmail.com

Mosquito/Malaria Control (31)
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Dear All,

Having watched this exchange for some time now, please allow me
to add a few comments.

Dear Bill, your statement is not accurate. Insecticide-Treated
BedNets (ITNs) have at least three important purposes in the
case of the infected person. 1) they protect the person from re-
infection (what you mentioned). 2) they prevent mosquitoes from
biting the infected person and so reduce the chance that the
parasite is passed onto other people. (An extremely important
outcome!) 3) They kill mosquitoes that land on or NEAR the ITN,
preventing other household members from being bitten, i.e. those
near, but not under, nets. Given the small size of most homes, 1
net might have considerable and long-lasting impact.

Field research proves the effectiveness of ITNs, in the above 3
ways, in helping to "breaking the chain of transmission." In
community-wide trials in several African settings, ITNs reduced
all-cause mortality by about 20%! Also, the push is to use long-
lasting ITNs, (LLINs), which last about 3 years. LLINs are more
practical than regular ITNs, which had to be re-treated every 6
months. Research in the field clearly shows ITNs offer important
protection to all community members, even those who do not sleep
under the nets. This is because they both protect from infection
and reduce the spread of infection (as mentioned above). Of
course, they must be coupled with prompt treatment of effective
anti-malarial medications.

Additionally, ITNs are being freely distributed in several major
vaccination campaigns, to help ensure a critical mass (i.e.
enough to be effective) are introduced into communities (e.g. in
Togo, Zambia and Ghana). The International Red Cross/Red Cres-
cent found that in Ghana before distribution of ITNs in a cam-
paign, 20.1% of families had an ITN and 6.0% of children slept
under an ITN. Post-distribution, 80.1% of children slept in a
home with an ITN! The work of the Red Cross on the ground, to
explain to families the importance of bednets and to show how
the use nets effectively, helps build such long-term behavior
changes.

Certain types of spraying (e.g. IRS) is often an excellent co-
intervention, BUT only if its use is evidence-based and only if
it is done properly. While the first criteria can be determined
fairly easily, ensuring the second is met is a bigger problem.
For example, EFFECTIVE indoor spraying requires exactly the cor-
rect amount of insecticide applied to the walls and just before
the biting season begins; this rarely happens. Even when I par-
ticipated in careful and extensive training sessions to show
proper application techniques, people get tired, begin to speed
up as a day wears on, forget to recalibrate sprayers, etc.. The
result is too little application of insecticide. Not only will
the protective effect wear off before the end of the biting sea-
son, but low levels of insecticide allow mosquitoes to develop
resistance to insecticides. And all spraying must be reapplied
every few months, compared to LLINs which last up to 3 years.

A second problem of IRS and outdoor spraying (e.g. larvaciding &
aerial spraying) is the difficulty of putting in place the
needed infrastructure to make sure spraying is done correctly
and that sufficient supplies are in place when/where needed. Few
African countries have a strong enough distribution and supply
system to move insecticides around fast enough to guarantee that
sufficient stocks are available when needed. YES, money must be
spent to rapidly build up this capacity. But UNTIL the capacity
is there alternatives must be used now to save lives today. This
is one reason that RBM feels aerial spraying has little practi-
cal application at this time, in Africa, when compared with
other interventions that can reduce death and illness today.

Finally, training costs are ALWAYS greatly underestimated.
Training sprayers is not enough. Success requires strong systems
of supervision, as well as realistic and meaningful compensation
systems so that workers are motivated to spray correctly. Actual
training costs a lot of money and takes a significant period of
time. Short-cuts do not work, and often poorly-trained community
workers are unfairly blamed when effective spraying techniques
are not followed! Aerial spraying requires exact timing and up-
to-date and accurate maps that show mosquito breeding areas.
Such mapping needs to be done, but is not yet available in most
places. The wide-spread use of ITNs can help buy the time to in-
vest in longer-term solutions based on local needs, conditions
and local wishes.

Prevention is only half the battle. To quickly reduce death and
illness, prevention must be combined with equitable, rapid and
universal access to effective treatment. When effective treat-
ment is combined with effective prevention, the chain of infec-
tion is broken. This many-sided approach (multi-method mosquito
control and rapid, effective treatment) is what worked in North
America, not simply widespread spraying.

Best regards,
Tom O'Connell
mailto:tsoconnell2@yahoo.com

(Note: While I was privileged to work with the RBM Secretariat
and other RBM partners, I do not now do so. My opinions are
strictly my own and do not represent any other person or group's
view.)

Mosquito/Malaria Control (32)
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I think what Dr. Isaac says has a lot of sense in it. I shall
vote for his idea.

A multi pronged approach - local herbs, mosquito repellants,
spraying and bed nets could be a good combination. The efficacy
of which has to be studied in the long term and improvements
made or wastages reduced in each area.

We tried using mosquito nets in coastal India. The weather is
already awful, stuffy and sticky - more inside a net - suffoca-
tion; some have a phobia of net!!

We use goodnight liquid or mat or worse some burning coil which
emits smoke - and make us cough most of the time!!!

But these are better than getting malaria!!

Can anyone help to prepare a clear and objective action plan
without any partisan feelings, except for the true eradication
of malaria in urban, semi-urban, rural, etc areas?

Thanks in advance to the good Samaritans.

Kris Dev
mailto:krisdev@gmail.com

Mosquito/Malaria Control (35)
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Dr Kigozi,

I have lived through several bouts with malaria and my wife
nearly died from an attack of falciparum that was resistant to
all the drugs.

As I have stated here in the past, what we are proposing is a
multi-pronged attack. This is patterned after the methodologies
used in the southern USA for the last 60-70 years with the con-
sequent complete eradication of endemic malaria. There is no
reason the same methods can't be applied to tropical Africa.

We are proposing beginning operations in Monrovia, Liberia.
There is probably no location on Earth with a higher incidence
of malaria. This is due to the 15,000 acres of swamp in the cen-
ter of the city. The insecticides to be used on a project such
as this would consist of organo-phosphates, pyrethroids, insect
larva growth regulators and larva specific bacteria. The adulti-
cides would be applied at rates of about 1/2 ounce per acre,
initially about three times a month. Once control is gained of
the Monrovian mosquito population the project becomes one of
maintenance, based on insect monitoring.

There is really nothing mysterious or experimental about this.
All I can say is to do you own research into the activities of
mosquito control districts in the USA, Europe, Australia, etc.

Bill Nesler
mailto:sdbc@hur.midco.net

Mosquito/Malaria Control (36)
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Hi Tom,

Believe it or not, I agree with most of what you have to say. To
begin, I may have mispoken about the proper application of bed-
nets. The proper use prevents the mosquito from contracting the
parasite and, as you said, "an extremely important outcome."
Your other concerns are the same things that we address in our
proposals. The team that has been put together has long experi-
ence in insect control operations, both on the ground and by
air. We have long experience in Africa and understand the inher-
ent problems with logistics. Our entomological team would take
the lead in monitoring and recommending timing and locations to
be treated. Our proposals are many pronged: aerial ULV, ground
ULV, larvaciding, IRS, source reduction and public education.
This is all stuff that has been done in the US for decades. I
would suggest researching the current operations in Darwin, Aus-
tralia (a tropical location).

Bill Nesler
mailto:sdbc@hur.midco.net

Mosquito/Malaria Control (37)
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Dear Tom and others,

Thanks for your careful thoughts and points in favor of use of
ITN and case-management. I do not see anyone contradicting to
what you said. And you are not contradicting what others said
either. We are looking for a longterm strategy built on your
short term approach. This is what lacking in RBM strategy and
putting money and resources towards that goal. Donors wants num-
ber of lives saved, number of cases averted against their in-
vestment and WHO/Unicef are good at that calculation.

You could have been louder for a long term solution rather than
pointing constraints. We have spent 4 billion dollars for Polio
eradication and money for that has been given by national and
international communities and people worldwide; because public
health experts put forward the strategy as a long term solution.
There were many constraints in putting the pieces for eradica-
tion but investments were made for effective surveillance, lo-
gistics and cold chain management, training, social mobiliza-
tion, public-private mix and so on.

Control for diarrheal illness is also facing similar problem
ended with personal hygiene and ORT with millions of episodes
occurring every year without investing on water, environment and
sanitation for a long lasting solution or towards that goal. As
mortality has gone down with use of ORT, the job is apparently
done.

Current outbreak of Dengue in Singapore is calling for a fresh
look at vector control. Will you be advocating ITN and case-
management as the only solution? Let us see what CDC advocate
for Katrina affected areas for vector control (particularly West
Nile Virus).

We are not sure if RBM has the expertise/capacity or courage to
go beyond what they are doing now.

Good discussion and I have been learning everyday. Bill and oth-
ers, keep the pressure up.

Best regards,

Mizan Siddiqi
Public Health Specialist
mailto:msiddiqi@voxiva.net