E-drug: Antidiarrhoeal Ercefuryll (cont'd)
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Nofuroxazide is the INN. Martindale 31st ed simply states that
nifuroxazide is an antibacterial agent that has been given by mouth in
a dose of 800mg daily in the treatment of colitis and diarrhoea. It is
poorly absorbed from the GI tract.
So then you have all the routine arguments against using an
antibacterial agent as an antidiarrhoeal.
Tim Dodd
Director of Pharmacy,
ShaukatKhanum Memorial Cancer Hospital, Lahore, Pakistan
timdodd@brain.net.pk
[Note: For anybody interested in the place of drugs in the management
of diarrhoea, there is the valuable WHO publication "The Rational Use
of Drugs in the Management of Acute Diarrhoea in Children" WHO, 1990.
To be ordered from WHO Geneva (SwFr 14; for developing countries
SwFr 9.80). Hilbrand Haak, E-drug moderator]
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