E-DRUG: Chloroquine therapeutic levels
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Dear all,
Can anybody help me to find the therapeutic range of chloroquine in
WHOLE blood? I have found therapeutic concentrations of chloroquine
in plasma, but not in whole blood and one reference states that
following oral administration of chloroquine, whole blood
concentrations are 8 to 10 times higher than those observed in plasma.
We need this information to detemine whether a 18-month old child
with a whole blood chloroquine concentration of 0.09mg/100ml is
in the toxic range or not.
Thank you
Annoesjka Chanterie
Drug Information Pharmacist
Medicines Information Centre
Department of Pharmacology
University of Cape Town
Observatory
7925
South Africa
Ph +27 21 4066280
Fax +27 21 4480503
E-mail: achanter@ uctgsh1.uct.ac.za
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