E-DRUG: Table of contents of Prescrire International, October 99 -
Volume 8 Nr. 43
Prescrire International is the English language edition of La revue
Prescrire. It consists of a selection of articles of international interest
from the monthly French-language journal La revue Prescrire. Prescrire
International contains evaluations of new drugs and new indications,
information on adverse effects, and assessments of therapeutic
interventions.
EDITORIAL
Orphan drug research
NEW PRODUCTS
Montelukast (new preparation)
No demonstrated role in the management of asthma
Olanzapine (new preparation)
No better risk-benefit ratio than with other neuroleptics
Tretinoin and cutaneous photoageing (new preparation)
Poorly effective and risky: don't prescribe!
Topiramate (new indication)
Helpful for children with partial epilepsy and
at all ages in tonic-clonic epilepsy
Ticlopidine (a second look)
No further use after stroke and in intermittent claudication
ADVERSE EFFECTS
Late cardiotoxicity of anthracyclines
Increases with cumulative doses and can lead to heart failure
REVIEWS
Management of type 2 diabetes
Glibenclamide for non overweight patients,
metformin for overweight patients
Fractures in adults on systemic steroid therapy
Clinically effective prophylaxis is lacking
Serotonin reuptake inhibitor antidepressants and pregnancy
Data are limited, and most involve fluoxetine
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