E-DRUG: Table of contents of Prescrire International, August 1998

E-drug: Table of contents of Prescrire International, August 1998
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Table of contents of Prescrire International, August 1998 - Volume 7 �
Nr. 36

Prescrire International is the English language edition of La revue
Prescrire. It consists of a selection of articles of international interest
from the monthly French-language journal La revue Prescrire. Prescrire
International contains evaluations of new drugs and new indications,
information on adverse effects, and assessments of therapeutic
interventions.

Editorial
New, or just new-fangled?

New Products
Tiagabine (new preparation)
Possibly helpful for multiresistant epileptic patients

Cefpodoxime (new dosage)
Unproven dose regimen in recurrent pharyngitis

Intravenous pamidronic acid (new indications)
Useful palliative treatment for osteolysis

Clodronic acid (a second look)
No value in malignant osteolysis

Glimepiride (new preparation)
Just another sulphonylurea agent

Tacrolimus in the prevention of graft rejection (new indication)
Helpful alternative to ciclosporin

Fluoride and bone (a second look)
No place in primary or secondary prevention of osteoporosis

Venlafaxine (new preparation)
No advantage over available antidepressants

Adverse Effects

Severe hypertriglyceridaemia on tamoxifen
Does not challenge its positive risk-benefit ratio in breast cancer

Meloxicam and gastrointestinal toxicity
Cases of potentially severe reactions

Anorectic drugs: managing the risk of valve disease
Watch out for valve disease in exposed patients

Hepatic toxicity of the tiliquinol-tilbroquinol combination
An old product with a negative risk-benefit ratio in acute diarrhoea

Reviews

Cardiovascular risk of oral contraceptives
Low, and mainly in women with risk factors

Prevention of haemorrhagic disease of the newborn
Routine vitamin K1 administration is justified

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for students, and 360$ (FF1860) for commercial institutions.

Prescrire International
Association Mieux Prescrire
BP 459
75527 Paris Cedex 11
France
Tel. 33 1 47 00 94 45
Fax 33 1 48 07 87 32
email : international@prescrire.org

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