E-DRUG: Independent Drug and Healthcare Newsletter for January 2020
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Newsletter, January 2020
Independent Drug & Healthcare Newsletter from the non-profit journal Prescrire International
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In Prescrire's Spotlight this month
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FEATURED REVIEW Antiepileptics and pregnancy: potential long-term effects in children
Many women who could become pregnant are exposed to antiepileptic drugs. Yet most of the antiepileptic drugs taken by pregnant women expose the unborn child to the risk of malformations, fetotoxic effects and neonatal disorders. What are the long-term effects of the most widely used antieleptics on children exposed in utero, and how do they compare?
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FREE DOWNLOAD In the January issue of Prescrire International - Dapagliflozin in type 2 diabetes: no advance in terms of cardiovascular complications
In the "Reviews" section this month: what is dapagliflozin's harm-benefit balance in type 2 diabetes, in light of the results of a recent randomised, double-blind trial studying the drug's effect on cardiovascular outcomes?
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Persistent psychotic disorders: avoid combining neuroleptics
Combining oral neuroleptics cumulates adverse effects but offers no proven benefits.
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The common cold: echinacea purpurea is no better than placebo
There is no known drug, herbal medicine or other remedy that reduces the intensity or duration of cold symptoms and has a favourable harm-benefit balance.
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Vitamin B6: overdoses leading to neuropathies
With few exceptions, consuming vitamin B6 in addition to food has no medical justification and can lead to overdoses with peripheral neuropathies.
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ADVANCING HEALTHACARE POLICY Access to clinical study reports: EMA's transparency policy and disclosure of vital documents should not be scaled back (December 2019)
Prescrire and 30 other organisations argue in a joint open letter that EMA's transparency and access to documents policy should not be watered down: instead it deserves greater attention as it is a cornerstone for enlightened research and decision making, public scrutiny and trust in the European regulator.
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COMING SOON Enjoy these features, and more, in our upcoming issues
Drugs to avoid in 2020 - Baclofen and alcohol dependence Pembrolizumab in combination with cytotoxic drugs in certain types of lung cancer * SSRI antidepressants: persistent sexual dysfunction Interactions between ulipristal and hormonal contraception...
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