E-DRUG: Prescrire International n°154 - November 2014
------------------------------------------------------------------------------
PRESCRIRE INTERNATIONAL - Independent information by and for healthcare professionals
View complete contents:
http://english.prescrire.org/en/SummaryDetail.aspx?Issueid=154
In the November issue of Prescrire International:
* FEATURED REVIEW:
Type 2 diabetes and metformin. First choice for monotherapy: weak evidence of efficacy but well-known and acceptable adverse effects.
The efficacy of metformin in type 2 diabetes is still thinly documented in 2014. However, an abundance of data is now available on its adverse effects. The evidence is relatively weak, but long experience with the use of metformin has shown that its adverse effect profile is acceptable.
http://english.prescrire.org/en/81/168/49555/0/NewsDetails.aspx
* FREE DOWNLOAD:
Artesunate - the standard intravenous treatment for severe attacks of malaria.
Plasmodium falciparum malaria can be life-threatening, particularly in young children, migrants, travellers and pregnant women. This sample page from the "New Products" section of the November issue sums up the factors that make intravenous artesunate the treatment of choice for severe attacks of Plasmodium falciparium malaria.
SUMMARY:
- Intravenous artesunate is more effective in reducing mortality than injectable quinine.
- It also has a better adverse effect profile and is more convenient to use.
- Full marketing authorisation in the EU would improve access to this drug.
http://english.prescrire.org/en/81/168/49556/0/NewsDetails.aspx
©Prescrire 1 November 2014
Prescrire is a non-profit continuing education organisation, committed to better patient care. Prescrire is financed by its subscribers. No grants, no advertising. No shareholders, no sponsors.
Subscribe today and enjoy instant access to the full database of articles in English published in Prescrire International since 1992. Subscribing online is fast and easy.
http://english.prescrire.org/en/83/178/0/0/About.aspx
Sign up for our free newsletter:
http://english.prescrire.org/en/83/552/0/0/About.aspx
Regards,
Bruno Toussaint
Publishing Director, Prescrire
Website: english.prescrire.org
contact@prescrire.org>
international <international@prescrire.org>