E-drug: Table of contents Prescrire International, February 2000
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Table of contents Prescrire International, February 2000, Vol. 8, no 45
Prescrire International is the English language edition of La revue
Prescrire. It consists of a selection of articles of international interest
from the monthly French-language journal La revue Prescrire. Prescrire
International contains evaluations of new drugs and new indications,
information on adverse effects, and assessments of therapeutic
interventions.
EDITORIAL
Traps
NEW PRODUCTS
Cabergoline and hyperprolactinaemia (new preparation)
Better than bromocriptine in women with hyperprolactinaemia
Dalteparin (new treatment duration)
Benefits of 35-day prophylaxis are not established
Zanamivir (new preparation)
No clear benefit for patients with suspected influenza
Levonorgestrel (new preparation)
The emergency contraceptive with the best risk-benefit ratio
Acellular pertussis vaccines (new preparations)
Long-term efficacy in the general population is not yet established
Trimetazidine (a second look)
No proof of efficacy in angina, vertigo and tinnitus
ADVERSE EFFECTS
Visual field constriction on vigabatrin
Use of vigabatrin in epilepsy should be restricted
Valve disease and pulmonary arterial hypertension
due to appetite suppressants
Late but welcome withdrawal from the French market
Drug-induced stuttering
Antiepileptics and psychotropics are the most commonly incriminated
Severe cardiac arrhythmia on fexofenadine ?
In patients with QT prolongation or risk factors for torsades de pointes
REVIEWS
Hepatitis B vaccination in countries with low endemicity
Efficacy of mass vaccination programmes is inadequately established
Acellular pertussis vaccines
Safer but maybe slightly less effective
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