E-DRUG: Independent Drug and Healthcare Newsletter for March 2020
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Newsletter, March 2020
Independent Drug & Healthcare Newsletter from the non-profit journal
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In Prescrire's Spotlight this month
FEATURED REVIEW Darvadstrocel (Alofisel°) for complex perianal fistulae in Crohn's disease. A rash marketing authorisation decision
How effective is darvadstrocel (Alofisel°) in healing perianal fistulae after usual treatments have failed? Does it reduce the need for surgical intervention? And what are darvadstrocel's adverse effects?
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FREE DOWNLOAD In the March issue of Prescrire International: Dengue vaccine (Dengvaxia°). Not for large-scale use
Dengvaxia°, a vaccine containing live attenuated viruses expressing antigens of the 4 known dengue virus serotypes, has been granted marketing authorisation in the European Union. How do Prescrire's editors rate this vaccine's harm-benefit balance?
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Protecting patients: France's Transparency Committee steps in
As evidenced by Prescrire's annual update of drugs to avoid in the name of better patient care, many drugs remain authorised for years despite an unfavourable harm-benefit balance. How then can patients and community resources be protected?
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Painful endometriosis: initial treatment options
In the absence of urinary or intestinal symptoms, and if the patient is not planning to become pregnant any time soon, first try analgesics such as NSAIDs or paracetamol. Hormonal contraception or a levonorgestrel intrauterine device are other options.
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Rotarix° oral vaccine: wrong-route errors
The Rotarix° oral vaccine applicator has a deceptive syringe-like appearance, which has resulted in intramuscular injections being given in error.
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Independent information does exist, but deserves more attention and visibility
In a published response to the article "Pathways to independence: towards producing and using trustworthy evidence" published online at bmj.com ( BMJ 2019;367:l6576), Prescrire points out that independent sources of information do exist, and many, like Prescrire, are members of the International Society of Drug Bulletins.
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COMING SOON Enjoy these features, and more, in our upcoming issues
Denosumab in steroid-induced osteoporosis: not acceptable * Lithium during pregnancy * Pregabalin: suicides * Rapid diagnostic tests in acute pharyngitis * Drugs in 2019: a brief review * The Mediator° disaster: disseminating the concept of conflicts of interest...
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