E-drug: Table of contents Prescrire Int October 1998
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Table of contents of Prescrire International, October 1998 - Volume 7 �
Nr. 37
Prescrire International is the English language edition of La revue
Prescrire. It consists of a selection of articles of international interest
from the monthly French-language journal La revue Prescrire. Prescrire
International contains evaluations of new drugs and new indications,
information on adverse effects, and assessments of therapeutic
interventions.
EDITORIAL
Clinical end points first
NEW PRODUCTS
Thalidomide (new preparation)
Offers an advantage in type II lepra reactions and severe aphthous disease
Cidofovir (new preparation)
Possibly helpful for non sight-threatening CMV retinitis of AIDS
Transdermal fentanyl (new preparation)
Helpful alternative to morphine and to oral and subcutaneous routes
Nevirapine (new preparation)
Possibly helpful in second-line triple-drug anti-HIV regimens
Interferon beta-1a (new preparation)
Short-term benefit in some forms of multiple sclerosis
Valsartan (new preparation)
Just another second-line antihypertensive
Donepezil (new preparation)
Slight efficacy in Alzheimer's disease
ADVERSE EFFECTS
Birth defects due to topical adapalene and tretinoin
Several disturbing cases reported after cutaneous exposure
Toxicity of chloroform
Drugs with better risk-benefit ratios are available
REVIEWS
Hepatitis C
Limits and dose regimen of interferon alfa
Fracture prevention in elderly women
Treatment of osteoporosis is only one approach
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