E-DRUG: queries

Thank Dr.Joel Lexchin for your help. However;

1.- Is the oral absorption of furosemide and/or spironolactone affected in
patient with congestive cardiac failure or in patient with secondary
aldosteronism?

PLEASE, COULD YOU DATE ANY ARTICLE ABOUT THIS?

Yes. If the congestive heart failure is bad, there is also oedema in the
wall of the intestine which decreases oral absorption of medications.

Sorry I cannot find a reference for this statement, but in talking to
several internists at my hospital they all agree with this statement.

Joel

Joel Lexchin MD
121 Walmer Rd.
Toronto, Ontario
CANADA M5R 2X8
Phone: (416)-964-7186
Fax: (416)-923-9515

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